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1

Adiponectin: Systemic contributor to insulin sensitivity

Utpal B. Pajvani, Philipp E. Scherer

Journal:

Current Diabetes Reports

Year:

2003

Language:

english

File:

PDF, 345 KB

english, 2003

2

Fat apoptosis through targeted activation of caspase 8: a new mouse model of inducible and reversible lipoatrophy

Pajvani, Utpal B, Trujillo, Maria E, Combs, Terry P, Iyengar, Puneeth, Jelicks, Linda, Roth, Kevin A, Kitsis, Richard N, Scherer, Philipp E

Journal:

Nature Medicine

Year:

2005

Language:

english

File:

PDF, 851 KB

english, 2005

3

Characterization and development of RGD-peptide-modified poly(lactic acid-co-lysine) as an interactive, resorbable biomaterial

Alonzo D. Cook, Jeffrey S. Hrkach, Nicholas N. Gao, Ivette M. Johnson, Utpal B. Pajvani, Scott M. Cannizzaro, Robert Langer

Journal:

Journal of Biomedical Materials Research Part B: Applied Biomaterials

Year:

1997

Language:

english

File:

PDF, 216 KB

english, 1997

4

ERRATUM: Adiponectin acts in the brain to decrease body weight

Qi, Yong, Takahashi, Nobuhiko, Hileman, Stanley M, Patel, Hiralben R, Berg, Anders H, Pajvani, Utpal B, Scherer, Philipp E, Ahima, Rexford S

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 54 KB

english, 2004

5

Adiponectin acts in the brain to decrease body weight

Qi, Yong, Takahashi, Nobuhiko, Hileman, Stanley M, Patel, Hiralben R, Berg, Anders H, Pajvani, Utpal B, Scherer, Philipp E, Ahima, Rexford S

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 380 KB

english, 2004

6

DIFFERENTIAL GLYCOSYLATION OF INTERLEUKIN 2, THE MOLECULAR BASIS FOR THE NOD Idd3 TYPE 1 DIABETES GENE?

Patricia L Podolin, Mary Beth Wilusz, Rose M Cubbon, Utpal Pajvani, Christopher J Lord, John A Todd, Laurence B Peterson, Linda S Wicker, Paul A Lyons

Journal:

Year:

2000

Language:

english

File:

PDF, 512 KB

english, 2000

7

Calcium Signaling through CaMKII Regulates Hepatic Glucose Production in Fasting and Obesity

Lale Ozcan, Catherine C.L. Wong, Gang Li, Tao Xu, Utpal Pajvani, Sung Kyu Robin Park, Anetta Wronska, Bi-Xing Chen, Andrew R. Marks, Akiyoshi Fukamizu, Johannes Backs, Harold A. Singer, John R. Yates

Journal:

Cell Metabolism

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

8

Inhibition of Notch uncouples Akt activation from hepatic lipid accumulation by decreasing mTorc1 stability

Pajvani, Utpal B, Qiang, Li, Kangsamaksin, Thaned, Kitajewski, Jan, Ginsberg, Henry N, Accili, Domenico

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 879 KB

english, 2013

9

Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner

Pajvani, Utpal B, Shawber, Carrie J, Samuel, Varman T, Birkenfeld, Andreas L, Shulman, Gerald I, Kitajewski, Jan, Accili, Domenico

Journal:

Nature Medicine

Year:

2011

Language:

english

File:

PDF, 700 KB

english, 2011

10

Molecular pathophysiology of metabolic effects of antipsychotic medications

Ballon, Jacob S., Pajvani, Utpal, Freyberg, Zachary, Leibel, Rudolph L., Lieberman, Jeffrey A.

Journal:

Trends in Endocrinology & Metabolism

Year:

2014

Language:

english

File:

PDF, 655 KB

english, 2014

11

A Transgenic Mouse with a Deletion in the Collagenous Domain of Adiponectin Displays Elevated Circulating Adiponectin and Improved Insulin Sensitivity

Combs, Terry P., Pajvani, Utpal B., Berg, Anders H., Lin, Ying, Jelicks, Linda A., Laplante, Mathieu, Nawrocki, Andrea R., Rajala, Michael W., Parlow, Albert. F., Cheeseboro, Laurelle, Ding, Yang-Yang

Journal:

Year:

2004

Language:

english

File:

PDF, 868 KB

english, 2004

12

Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions

Qiang, Li, Kon, Ning, Zhao, Wenhui, Jiang, Le, Knight, Colette M., Welch, Carrie, Pajvani, Utpal, Gu, Wei, Accili, Domenico

Journal:

Year:

2015

Language:

english

File:

PDF, 3.52 MB

english, 2015

13

The new biology of diabetes

Pajvani, Utpal B., Accili, Domenico

Journal:

Year:

2015

Language:

english

File:

PDF, 1.69 MB

english, 2015

14

Erratum to: The new biology of diabetes

Pajvani, Utpal B., Accili, Domenico

Journal:

Year:

2015

Language:

english

File:

PDF, 180 KB

english, 2015

15

mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2

Kim, KyeongJin, Qiang, Li, Hayden, Matthew S., Sparling, David P., Purcell, Nicole H., Pajvani, Utpal B.

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 2.09 MB

english, 2016

16

“Free” Raptor – a novel regulator of metabolism

Kim, KyeongJin, Pajvani, Utpal B.

Journal:

Year:

2016

Language:

english

File:

PDF, 1.05 MB

english, 2016

17

Apoptosis Through Targeted Activation of Caspase8 (“ATTAC-mice”): Novel Mouse Models of Inducible and Reversible Tissue Ablation

Trujillo, Maria E., Pajvani, Utpal B., Scherer, Philipp E.

Journal:

Year:

2005

Language:

english

File:

PDF, 613 KB

english, 2005

18

Adipocyte-specific blockade of gamma-secretase, but not inhibition of Notch activity, reduces adipose insulin sensitivity

Sparling, David P., Yu, Junjie, Kim, KyeongJin, Zhu, Changyu, Brachs, Sebastian, Birkenfeld, Andreas L., Pajvani, Utpal B.

Journal:

Molecular Metabolism

Year:

2016

Language:

english

File:

PDF, 832 KB

english, 2016

19

Nonalcoholic fatty liver disease: cause or consequence of type 2 diabetes?

Valenti, Luca, Bugianesi, Elisabetta, Pajvani, Utpal, Targher, Giovanni

Journal:

Liver International

Year:

2016

Language:

english

File:

PDF, 501 KB

english, 2016

20

Degradation of PHLPP2 by KCTD17, via a Glucagon-dependent Pathway, Promotes Hepatic Steatosis

Kim, KyeongJin, Ryu, Dongryeol, Dongiovanni, Paola, Ozcan, Lale, Nayak, Shruti, Ueberheide, Beatrix, Valenti, Luca, Auwerx, Johan, Pajvani, Utpal B.

Journal:

Gastroenterology

Year:

2017

Language:

english

File:

PDF, 5.67 MB

english, 2017

21

MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling

Bartolomé, Alberto, García-Aguilar, Ana, Asahara, Shun-Ichiro, Kido, Yoshiaki, Guillén, Carlos, Pajvani, Utpal B., Benito, Manuel

Journal:

Molecular and Cellular Biology

Year:

2017

Language:

english

File:

PDF, 4.33 MB

english, 2017

22

Pathophysiology of drug induced weight and metabolic effects: findings from an RCT in healthy volunteers treated with olanzapine, iloperidone, or placebo

Ballon, Jacob S, Pajvani, Utpal B, Mayer, Laurel ES, Freyberg, Zachary, Freyberg, Robin, Contreras, Ignacio, Rosenbaum, Michael, Leibel, Rudolph L, Lieberman, Jeffrey A

Journal:

Journal of Psychopharmacology

Year:

2018

Language:

english

File:

PDF, 257 KB

english, 2018

23

Inhibition of NAPDH Oxidase 2 (NOX2) Prevents Oxidative Stress and Mitochondrial Abnormalities Caused by Saturated Fat in Cardiomyocytes

Joseph, Leroy C., Barca, Emanuele, Subramanyam, Prakash, Komrowski, Michael, Pajvani, Utpal, Colecraft, Henry M., Hirano, Michio, Morrow, John P., Essop, M.Faadiel

Journal:

Year:

2016

Language:

english

File:

PDF, 3.08 MB

english, 2016

24

Hypoglycemia Secondary to Sulfonylurea Ingestion in a Patient with End Stage Renal Disease: Results from a 72-Hour Fast

Abraham, Alice, Rubin, Mishaela, Accili, Domenico, Bilezikian, John P., Pajvani, Utpal B.

Journal:

Case Reports in Endocrinology

Year:

2015

Language:

english

File:

PDF, 1.75 MB

english, 2015

25

Diabetes Insipidus Associated with Hemophagocytic Lymphohistiocytosis: First Case Report

Pajvani, Utpal, Lipton, Michael, Grajower, Martin

Journal:

Endocrine Practice

Year:

2011

File:

PDF, 599 KB

2011

26

Dietary Saturated Fat Promotes Arrhythmia by Activating NOX2 (NADPH Oxidase 2)

Joseph, Leroy C., Avula, Uma Mahesh R., Wan, Elaine Y., Reyes, Michael V., Lakkadi, Kundanika R., Subramanyam, Prakash, Nakanishi, Koki, Homma, Shunichi, Muchir, Antoine, Pajvani, Utpal B., Thorp, Edw

Journal:

Circulation Arrhythmia and Electrophysiology

Year:

2019

Language:

english

File:

PDF, 934 KB

english, 2019

27

Notch signaling dynamically regulates adult β cell proliferation and maturity

Bartolome, Alberto, Zhu, Changyu, Sussel, Lori, Pajvani, Utpal B.

Journal:

The Journal of clinical investigation

Year:

2018

File:

PDF, 14.01 MB

2018

28

Mechanisms of Fibrosis Development in NASH

Schwabe, Robert F., Tabas, Ira, Pajvani, Utpal B.

Journal:

Gastroenterology

Year:

2020

File:

PDF, 4.86 MB

2020

29

Cholesterol Stabilizes TAZ in Hepatocytes to Promote Experimental Non-alcoholic Steatohepatitis

Wang, Xiaobo, Cai, Bishuang, Yang, Xiaoming, Sonubi, Oluwatoni O., Zheng, Ze, Ramakrishnan, Rajasekhar, Shi, Hongxue, Valenti, Luca, Pajvani, Utpal B., Sandhu, Jaspreet, Infante, Rodney E., Radhakrish

Journal:

Cell Metabolism

Year:

2020

File:

PDF, 5.37 MB

2020

30

An Ultradian Notch in Beta-Cell Development

Phimister, Elizabeth G., Pajvani, Utpal B., Sussel, Lori

Journal:

New England Journal of Medicine

Year:

2020

File:

PDF, 3.31 MB

2020

31

Inhibition of Î³-secretase in adipocytes leads to altered IL-6 secretion and adipose inflammation

Sparling, David P., McCullough, Nile, Pajvani, Utpal, Humphrey, Mary Beth

Journal:

Year:

2020

File:

PDF, 2.40 MB

2020

32

Notch activity characterizes a common hepatocellular carcinoma subtype with unique molecular and clinicopathologic features

Zhu, Changyu, Ho, Yu-Jui, Salomao, Marcela A., Dapito, Dianne H., Bartolome, Alberto, Schwabe, Robert F., Lee, Ju-Seog, Lowe, Scott W., Pajvani, Utpal B.

Journal:

Journal of Hepatology

Year:

2020

File:

PDF, 8.43 MB

2020

33

Maladaptive regeneration â the reawakening of developmental pathways in NASH and fibrosis

Zhu, Changyu, Tabas, Ira, Schwabe, Robert F., Pajvani, Utpal B.

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2020

File:

PDF, 2.85 MB

2020

34

MTOR and Beta Cell Adaptation in T2D

Bartolome, Alberto, Pajvani, Utpal B

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2020

File:

PDF, 280 KB

2020

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